ARTIFICIAL SKIN--CULTURING OF DIFFERENT SKIN CELL LINES FOR GENERATING AN ARTIFICIAL SKIN SUBSTITUTE ON CROSS-WEAVED SPIDER SILK FIBRES.

Artificial skin--culturing of different skin cell lines for generating an artificial skin substitute on cross-weaved spider silk fibres.

BACKGROUND: In the field of Plastic Reconstructive Surgery the development of new innovative matrices for skin repair is in urgent need.The ideal biomaterial should promote attachment, proliferation and growth of cells.Additionally, it should degrade in an appropriate time period without releasing harmful substances, but not exert a pathological im

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Improving the Antigenicity of SARS-CoV-2 Vaccine Genes by Merging Mutations from Different Variants of Concern

During the COVID-19 pandemic, the early emergence of viral variants repeatedly undermined the effects of vaccination.Our aim here is to explore strategies for improving spike vaccine gene antigenicity by merging mutations from different variants of concern (VOCs) in a single vaccine gene.To this end, newly developed recombinant vaccine genes were d

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